Pilot study on recurrent aphthous stomatitis (RAS): a randomized placebo-controlled trial for the comparative therapeutic effects of systemic prednisone and systemic montelukast in subjects unresponsive to topical therapy.

@article{Femiano2010PilotSO,
  title={Pilot study on recurrent aphthous stomatitis (RAS): a randomized placebo-controlled trial for the comparative therapeutic effects of systemic prednisone and systemic montelukast in subjects unresponsive to topical therapy.},
  author={Felice Femiano and Curzio Buonaiuto and Fernando Gombos and Alessandro Lanza and Nicola Cirillo},
  journal={Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics},
  year={2010},
  volume={109 3},
  pages={402-7}
}
BACKGROUND Recurrent aphthous stomatitis (RAS) is characterized by recurrent painful oral ulcers whose etiology remains largely unknown. Numerous therapeutic protocols have been tried so far, but effectiveness remains an issue. OBJECTIVE To test a new drug for patients with recurrent oral aphthae nonresponsive to local corticosteroid therapy, we compared the therapeutic effectiveness and adverse effects of systemic prednisone and systemic montelukast in a placebo-controlled trial. STUDY… CONTINUE READING

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