Pilot study on n-3 polyunsaturated fatty acids in the treatment of human experimental gingivitis.

@article{Campan1997PilotSO,
  title={Pilot study on n-3 polyunsaturated fatty acids in the treatment of human experimental gingivitis.},
  author={Pierre Campan and P O Planchand and D G{\'o}mez-Pastrana Dur{\'a}n},
  journal={Journal of clinical periodontology},
  year={1997},
  volume={24 12},
  pages={907-13}
}
The anti-inflammatory effect of n-3 PUFA on the gingivae has already been demonstrated in animal models. The aim of this double-blind, randomized pilot study versus placebo is to evaluate this action in human experimentally-induced gingivitis. For 14 days (D0-D14), 37 healthy volunteers practised intensive oral hygiene, then abstained from brushing their teeth for 21 days (D14 to D35). On D28, the patients were randomized into 2 groups: 18 received the drug (fish oil: 30% n-3 PUFA) and 19… CONTINUE READING