Pilot study of oral valganciclovir therapy in patients with classic Kaposi sarcoma.

@article{Krown2011PilotSO,
  title={Pilot study of oral valganciclovir therapy in patients with classic Kaposi sarcoma.},
  author={Susan E. Krown and Dirk P. Dittmer and Ethel Cesarman},
  journal={The Journal of infectious diseases},
  year={2011},
  volume={203 8},
  pages={
          1082-6
        }
}
We conducted a clinical trial of oral valganciclovir, a drug with in vitro activity against Kaposi sarcoma (KS)-associated herpesvirus (KSHV), in classic KS. Five human immunodeficiency virus-seronegative participants received valganciclovir for up to six 4-week cycles at doses used for cytomegalovirus infection. None of the study subjects showed an objective response; KS progressed in 4 subjects after 1-4 cycles and remained stable in 1 subject after 6 cycles. KS biopsies showed minimal lytic… CONTINUE READING
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- associated Kaposi ’ s sarcoma

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