Pilot study of antithymocyte globulin in systemic sclerosis.

  title={Pilot study of antithymocyte globulin in systemic sclerosis.},
  author={Eric L Matteson and Mohammed I Shbeeb and Timothy G. McCarthy and Kenneth T Calamia and Lester E Mertz and J{\"o}rg J Goronzy},
  journal={Arthritis and rheumatism},
  volume={39 7},
OBJECTIVE Between June 1, 1992 and August 31, 1994 we conducted an open pilot study of antithymocyte globulin (ATGAM; Upjohn, Kalamazoo, MI) in 10 patients with early systemic sclerosis (SSc) to assess whether this agent might prevent the progression of cutaneous and pulmonary involvement in this disease. METHODS Adult patients with early SSc (< 3 years) and evidence of progressive skin and pulmonary disease were enrolled. All patients were hospitalized and received a single course of… CONTINUE READING


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