Pilot study: peripheral biomarkers for diagnosing sporadic Parkinson’s disease

@article{Grnblatt2010PilotSP,
  title={Pilot study: peripheral biomarkers for diagnosing sporadic Parkinson’s disease},
  author={E. Gr{\"u}nblatt and S. Zehetmayer and C. Jacob and T. M{\"u}ller and W. Jost and P. Riederer},
  journal={Journal of Neural Transmission},
  year={2010},
  volume={117},
  pages={1387-1393}
}
The need for an early and differential diagnosis of Parkinson’s disease (PD) is undoubtedly one of the main quests of the century. An early biomarker would enable therapy to begin sooner and would, hopefully, slow or better prevent progression of the disease. We performed transcript profiling via quantitative RT-PCR in RNA originating from peripheral blood samples. The groups were de novo (n = 11) and medicated PD (n = 94) subjects and healthy controls (n = 34), while for negative control… Expand
A molecular signature in blood identifies early Parkinson’s disease
Parkinson's disease: molecular risk factors.
  • E. Grünblatt
  • Biology, Medicine
  • Parkinsonism & related disorders
  • 2012
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