Pilot study: fibrin sealant in anal fistula model.

  title={Pilot study: fibrin sealant in anal fistula model.},
  author={Gordon N Buchanan and Paul D. Sibbons and Mike Osborn and Clive I. Bartram and Tahera Ansari and Steve Halligan and Charles Richard Cohen},
  journal={Diseases of the colon and rectum},
  volume={48 3},
PURPOSE The aim of this study was to investigate the failure of fibrin sealant treatment for fistula-in-ano in an experimental porcine model and to determine histologic changes associated with the sealant and setons. METHODS Three surgically created fistulas were treated by seton drainage in each of eight male pigs. After 26 days, magnetic resonance imaging was performed and setons were removed. Two pigs were killed as controls for stereologic histologic fistula track assessment. In six… CONTINUE READING
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