Pilot randomized trial of selective internal radiation therapy vs. chemoembolization in unresectable hepatocellular carcinoma.

@article{Kolligs2015PilotRT,
  title={Pilot randomized trial of selective internal radiation therapy vs. chemoembolization in unresectable hepatocellular carcinoma.},
  author={Frank Thomas Kolligs and J. I. Bilbao and Tobias F. Jakobs and Mercedes I{\~n}arrairaegui and Jutta Maria Nagel and Macarena Rodr{\'i}guez and Alexander R Haug and Delia D'Avola and Mark op den Winkel and Antonio Mart{\'i}nez-Cuesta and Christoph Gregor Trumm and Ana Calvo Benito and Klaus Tatsch and Christoph J. Zech and Ralf-Thorsten Hoffmann and Bruno Sangro},
  journal={Liver international : official journal of the International Association for the Study of the Liver},
  year={2015},
  volume={35 6},
  pages={
          1715-21
        }
}
BACKGROUND & AIMS To compare selective internal radiation therapy (SIRT) with transarterial chemoembolization (TACE), the standard-of-care for intermediate-stage unresectable, hepatocellular carcinoma (HCC), as first-line treatment. METHODS SIRTACE was an open-label multicenter randomized-controlled pilot study, which prospectively compared primarily safety and health-related quality of life (HRQoL) changes following TACE and SIRT. Patients with unresectable HCC, Child-Pugh ≤B7, ECOG… CONTINUE READING
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