Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.

@article{Vitetta2012PilotPI,
  title={Pilot phase IB clinical trial of an alhydrogel-adsorbed recombinant ricin vaccine.},
  author={Ellen S. Vitetta and Joan E. Smallshaw and John D Schindler},
  journal={Clinical and vaccine immunology : CVI},
  year={2012},
  volume={19 10},
  pages={1697-9}
}
There is no FDA-approved vaccine for the potent plant toxin ricin. We have developed a recombinant ricin vaccine, RiVax. Without adjuvant it is safe and immunogenic in mice, rabbits, and humans. Based on our studies in mice, we now report the results of a small clinical trial with Alhydrogel-adsorbed RiVax. 

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