Pili in Gram-negative and Gram-positive bacteria — structure, assembly and their role in disease

@article{Proft2008PiliIG,
  title={Pili in Gram-negative and Gram-positive bacteria — structure, assembly and their role in disease},
  author={Thomas Proft and Edward N Baker},
  journal={Cellular and Molecular Life Sciences},
  year={2008},
  volume={66},
  pages={613-635}
}

• Thomas Proft, Edward N Baker
• Published 2008 in Cellular and Molecular Life Sciences
• DOI:10.1007/s00018-008-8477-4

Many bacterial species possess long filamentous structures known as pili or fimbriae extending from their surfaces. Despite the diversity in pilus structure and biogenesis, pili in Gram-negative bacteria are typically formed by non-covalent homopolymerization of major pilus subunit proteins (pilins), which generates the pilus shaft. Additional pilins may be added to the fiber and often function as host cell adhesins. Some pili are also involved in biofilm formation, phage transduction, DNA… CONTINUE READING

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