PilZ Domain Protein FlgZ Mediates Cyclic Di-GMP-Dependent Swarming Motility Control in Pseudomonas aeruginosa.

@article{Baker2016PilZDP,
  title={PilZ Domain Protein FlgZ Mediates Cyclic Di-GMP-Dependent Swarming Motility Control in Pseudomonas aeruginosa.},
  author={Amy E. Baker and Andreas Diepold and Sherry L. Kuchma and Jessie E. Scott and Dae Gon Ha and Giulia Orazi and Judith P. Armitage and George A O'Toole},
  journal={Journal of bacteriology},
  year={2016},
  volume={198 13},
  pages={
          1837-46
        }
}
UNLABELLED The second messenger cyclic diguanylate (c-di-GMP) is an important regulator of motility in many bacterial species. In Pseudomonas aeruginosa, elevated levels of c-di-GMP promote biofilm formation and repress flagellum-driven swarming motility. The rotation of P. aeruginosa's polar flagellum is controlled by two distinct stator complexes, MotAB, which cannot support swarming motility, and MotCD, which promotes swarming motility. Here we show that when c-di-GMP levels are elevated… CONTINUE READING
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