PilC of pathogenic Neisseria is associated with the bacterial cell surface.

@article{Rahman1997PilCOP,
  title={PilC of pathogenic Neisseria is associated with the bacterial cell surface.},
  author={Mokhlasur Rahman and Helena K{\"a}llstr{\"o}m and Staffan J. Normark and A B Jonsson},
  journal={Molecular microbiology},
  year={1997},
  volume={25 1},
  pages={11-25}
}
Adherence of pathogenic Neisseria to target host cells is mediated by pili. PilC1 and PilC2 are two high-molecular-weight proteins involved in pilus assembly and cellular adherence functions of the pili. Inactivation of pilC1 or pilC2 in N. meningitidis resulted in clones that expressed the same number of pili as the parent, contained no alterations in pilE and showed no detectable differences in PilE glycosylation. However, the PilC2+ pilC1- mutant showed much reduced adherence to target cells… CONTINUE READING

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