Pil1 controls eisosome biogenesis.

  title={Pil1 controls eisosome biogenesis.},
  author={Karen E. Moreira and Tobias C. Walther and Pablo S. Aguilar and Peter J. Walter},
  journal={Molecular biology of the cell},
  volume={20 3},
The molecular composition of plasma membranes is constantly remodeled by endocytosis and exocytosis. Eisosomes are large cytoplasmic protein assemblies that localize to specialized domains on the yeast plasma membrane. They are of uniform size and immobile, and their disruption leads to large aberrant plasma membrane invaginations and endocytic defects. It is unknown how eisosomes are formed or inherited and what governs their size, distribution, and location. Here we show that eisosomes are… CONTINUE READING

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