Pigs with the dominant white coat color phenotype carry a duplication of the KIT gene encoding the mast/stem cell growth factor receptor

@article{Moller1996PigsWT,
  title={Pigs with the dominant white coat color phenotype carry a duplication of the KIT gene encoding the mast/stem cell growth factor receptor},
  author={M. Johansson Moller and Renuka Chaudhary and Eva Hellm{\'e}n and B. H{\"o}yheim and Bhanu Chowdhary and Leif Andersson},
  journal={Mammalian Genome},
  year={1996},
  volume={7},
  pages={822-830}
}
Comparative mapping data suggested that the dominant white coat color in pigs may be due to a mutation in KIT which encodes the mast/stem cell growth factor receptor. We report here that dominant white pigs lack melanocytes in the skin, as would be anticipated for a KIT mutation. We found a complete association between the dominant white mutation and a duplication of the KIT gene, or part of it, in samples of unrelated pigs representing six different breeds. The duplication was revealed by… CONTINUE READING
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