Pigmented epithelium to retinal transdifferentiation and Pax6 expression in larval Xenopus laevis.

@article{Arresta2005PigmentedET,
  title={Pigmented epithelium to retinal transdifferentiation and Pax6 expression in larval Xenopus laevis.},
  author={Emiliano Arresta and Sergio Bernardini and Enrico Bernardini and Sergio Filoni and Stefano Maria Cannata},
  journal={Journal of experimental zoology. Part A, Comparative experimental biology},
  year={2005},
  volume={303 11},
  pages={958-67}
}
This study examines the retinal transdifferentiation (TD) of retinal pigmented epithelium (RPE) fragments dissected from Xenopus laevis larvae and implanted into the vitreous chamber of non-lentectomized host eyes. In these experimental conditions, most RPE implants transformed into polarized vesicles in which the side adjacent to the lens maintained the RPE phenotype, while the side adjacent to the host retina transformed into a laminar retina with the photoreceptor layer facing the cavity of… CONTINUE READING

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