Pigmented cutaneous papillomatosis (pigmented epidermal nevus) in three pug dogs; histopathology, electron microscopy and analysis of viral DNA by the polymerase chain reaction.

@article{Narama2005PigmentedCP,
  title={Pigmented cutaneous papillomatosis (pigmented epidermal nevus) in three pug dogs; histopathology, electron microscopy and analysis of viral DNA by the polymerase chain reaction.},
  author={Isao Narama and Yasuhiro Kobayashi and Tamotsu Yamagami and Kiyokazu Ozaki and Yasuko Ueda},
  journal={Journal of comparative pathology},
  year={2005},
  volume={132 2-3},
  pages={132-8}
}
Canine pigmented epidermal nevus (CPEN) is a skin disorder of some breeds of dog characterized by multiple black plaques of the haired and non-haired skin. Three cases of pigmented cutaneous papillomatosis (previously described also as CPEN) in pug dogs were investigated histopathologically, immunohistochemically and electron microscopically. Additionally, DNA analyses with the polymerase chain reaction (PCR) were performed in two cases. Many nuclei of the stratum granulosa were diffusely… CONTINUE READING