Pigmentation in Black-boned sheep (Ovis aries): association with polymorphism of the MC1R gene

@article{Deng2007PigmentationIB,
  title={Pigmentation in Black-boned sheep (Ovis aries): association with polymorphism of the MC1R gene},
  author={Weidong Deng and Wang Shu and S. L. Yang and X. W. Shi and Huaming Mao},
  journal={Molecular Biology Reports},
  year={2007},
  volume={36},
  pages={431-436}
}
Variations in vertebrate skin and hair color are due to varied amounts of eumelanin (brown/black) and phaeomelanin (red/yellow) produced by the melanocytes. The melanocortin 1 receptor (MC1R) is a regulator of eumelanin and phaeomelanin production in the melanocytes, and MC1R mutations causing coat color changes are known in many vertebrates. We have sequenced the entire coding region of the MC1R gene in Black-boned, Nanping indigenous and Romney Marsh sheep populations and found two silent… CONTINUE READING

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