Pigment epithelium-derived factor induces interleukin-10 expression in human macrophages by induction of PPAR gamma.

@article{Yang2010PigmentEF,
  title={Pigment epithelium-derived factor induces interleukin-10 expression in human macrophages by induction of PPAR gamma.},
  author={Su-Lin Yang and S Chen and Ju-Yun Wu and Tsung-Chuan Ho and Y. -P. Tsao},
  journal={Life sciences},
  year={2010},
  volume={87 1-2},
  pages={26-35}
}
AIM In search for the anti-inflammation mechanism of PEDF, we investigate whether pigment epithelium-derived factor (PEDF) induces the gene expression of interleukin (IL)-10 in human macrophages and determine the molecular basis of this induction. MAIN METHODS Human macrophages derived from a monocytic cell line, THP-1, and peripheral monocytes were treated with PEDF. IL-10 expression was assessed by quantitative real-time PCR, enzyme-linked immunosorbent assay, semi-quantitative reverse… CONTINUE READING

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Nuclear Factor of Activated T Cells Balances Angiogenesis Activation and Inhibition

The Journal of experimental medicine • 2004
View 7 Excerpts
Highly Influenced

Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 2006
View 6 Excerpts
Highly Influenced

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