Pigment dispersing factor-dependent and -independent circadian locomotor behavioral rhythms.

@article{Sheeba2008PigmentDF,
  title={Pigment dispersing factor-dependent and -independent circadian locomotor behavioral rhythms.},
  author={Vasu Sheeba and Vijay K Sharma and Huaiyu Gu and Yu-Ting Chou and Diane K. O'Dowd and Todd C Holmes},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2008},
  volume={28 1},
  pages={
          217-27
        }
}
Circadian pacemaker circuits consist of ensembles of neurons, each expressing molecular oscillations, but how circuit-wide coordination of multiple oscillators regulates rhythmic physiological and behavioral outputs remains an open question. To investigate the relationship between the pattern of oscillator phase throughout the circadian pacemaker circuit and locomotor activity rhythms in Drosophila, we perturbed the electrical activity and pigment dispersing factor (PDF) levels of the lateral… CONTINUE READING

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