Pigment Epithelium-Derived Factor Mediates Autophagy and Apoptosis in Myocardial Hypoxia/Reoxygenation Injury

@inproceedings{Kuo2016PigmentEF,
  title={Pigment Epithelium-Derived Factor Mediates Autophagy and Apoptosis in Myocardial Hypoxia/Reoxygenation Injury},
  author={Hsuan-Fu Kuo and Po-Len Liu and Inn-Wen Chong and Yu-Peng Liu and Yung-Hsiang Chen and P H Ku and Chia-Yang Li and Hsiu-Hua Chen and Hui-Ching Chiang and Chiao-Lin Wang and Huang-Jen Chen and Yen-Chieh Chen and Chong-Chao Hsieh},
  booktitle={PloS one},
  year={2016}
}
Pigment epithelium-derived factor (PEDF) is a multifunctional protein that exhibits anti-angiogenic, antitumor, anti-inflammatory, antioxidative, anti-atherogenic, and cardioprotective properties. While it was recently shown that PEDF expression is inhibited under low oxygen conditions, the functional role of PEDF in response to hypoxia/reoxygenation (H/R… CONTINUE READING