Piezophysiology of genome wide gene expression levels in the yeast Saccharomyces cerevisiae

  title={Piezophysiology of genome wide gene expression levels in the yeast Saccharomyces cerevisiae},
  author={Hitoshi Iwahashi and Hisayo Shimizu and Mine Odani and Yasuhiko Komatsu},
Hydrostatic pressure is one of the physical factors affecting cellular physiology. Hydrostatic pressure of a few hundred MPa decreases the viability of yeast cells, and pressure of a few tens MPa decreases the growth rate. To understand the effect of hydrostatic pressure, we employed yeast DNA microarrays and analyzed genome-wide gene-expression levels after the pressure treatment with 180 MPa (immediate) at 4°C and recovery incubation for 1 h and 40 MPa (16 h) at 4°C and recovery incubation… CONTINUE READING


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