Pieces of eight: bioactive fragments of extracellular proteins as regulators of angiogenesis.

@article{1997PiecesOE,
  title={Pieces of eight: bioactive fragments of extracellular proteins as regulators of angiogenesis.},
  author={},
  journal={Trends in cell biology},
  year={1997},
  volume={7 5},
  pages={182-6}
}
  • Published 1997 in Trends in cell biology
Specific stages of angiogenesis are regulated by extracellular proteins. This review discusses the endogenous proteolysis of eight of these proteins and the release of polypeptide fragments that have biological activities different from those of the native, parent protein. The generation of natural cleavage products could provide a precise mechanism for the regulation of angiogenesis. Although further experimental confirmation of this mechanism is needed, this leitmotif offers an attractive… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 47 extracted citations

Differential gene expression by endothelial cells in distinct angiogenic states.

European journal of biochemistry • 2000
View 4 Excerpts
Highly Influenced

Revisiting the matricellular concept

Matrix biology : journal of the International Society for Matrix Biology • 2014
View 3 Excerpts

Similar Papers

Loading similar papers…