Picosecond dynamics of a membrane protein revealed by 2D IR.

Abstract

Fast protein dynamics can be missed with techniques that have relatively slow observation times. Using 2D IR spectroscopy and isotope labeling, we have probed the rapid, picosecond dynamics of a membrane protein in its native environment. By measuring the homogeneous and inhomogeneous IR linewidths of 11 amide I modes (backbone carbonyl stretch), we have… (More)

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Cite this paper

@article{Mukherjee2006PicosecondDO, title={Picosecond dynamics of a membrane protein revealed by 2D IR.}, author={Prabuddha Mukherjee and Itamar Kass and Isaiah T. Arkin and Martin T Zanni}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2006}, volume={103 10}, pages={3528-33} }