Picobirnavirus infections: viral persistence and zoonotic potential.

  title={Picobirnavirus infections: viral persistence and zoonotic potential.},
  author={Balasubramanian Ganesh and K B{\'a}nyai and Vito Martella and Ferenc Jakab and Gisela Masachessi and Nobumichi Kobayashi},
  journal={Reviews in medical virology},
  volume={22 4},
Picobirnaviruses (PBVs) are small, non-enveloped, bisegmented double-stranded RNA genomic viruses of vertebrate hosts. Since their discovery in the late 1980s in clinical specimens from outbreaks of acute gastroenteritis in children, significant efforts have been made to investigate the role of PBV in diarrheic diseases. PBV has been detected in sporadic episodes of diarrhea as sole pathogen or coinfection as well as in outbreaks of acute gastroenteritis and in immunocompromised patients with… CONTINUE READING
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