Picenadol in a Large Multicenter Dental Pain Study

@article{Goldstein1994PicenadolIA,
  title={Picenadol in a Large Multicenter Dental Pain Study},
  author={David J. Goldstein and Rocco L. Brunelle and R E George and Stephen Andrew Cooper and Paul J. Desjardins and G. W. Gaston and G E Jeffers and L T Gallegos and Donald C. Reynolds},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  year={1994},
  volume={14}
}
Study Objective. To estimate the analgesic dose of picenadol hydrochloride equal to codeine 60 mg in a dental pain model. 
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2 Citations
Background Citations
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2 Citations

Pain-mediated altered absorption and metabolism of ibuprofen: an explanation for decreased serum enantiomer concentration after dental surgery.
TLDR
Surgery for wisdom tooth removal resulted in substantial decreases in the serum concentration of ibuprofen enantiomers and a prolongation in the time to peak concentration, suggesting reduced absorption and altered metabolism are the likely cause of these changes.
Drug disease interactions: role of inflammatory mediators in pain and variability in analgesic drug response.
  • K. Kulmatycki, F. Jamali
  • Medicine, Biology
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
  • 2007
TLDR
Patients with temporal mandibular joint disease with increased expression of interleukins prior to treatment demonstrate inadequate pain relief after administration of anti-TNF-.

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TLDR
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