Phytotoxic and Antifungal Compounds from Two Apiaceae Species, Lomatium californicum and Ligusticum hultenii, Rich Sources of Z-ligustilide and Apiol, Respectively

@article{Meepagala2005PhytotoxicAA,
  title={Phytotoxic and Antifungal Compounds from Two Apiaceae Species, Lomatium californicum and Ligusticum hultenii, Rich Sources of Z-ligustilide and Apiol, Respectively},
  author={Kumudini M Meepagala and George Sturtz and David Earl Wedge and Kevin K. Schrader and Stephen O. Duke},
  journal={Journal of Chemical Ecology},
  year={2005},
  volume={31},
  pages={1567-1578}
}
The seeds of two Apiaceae species, Ligusticum hultenii and Lomatium californicum, were investigated. Preliminary bioassays indicated that methylene chloride extracts of seeds of both species contained selective phytotoxic activity against monocots and antifungal activity against Colletotrichum fragariae. Active constituents were isolated by bioassay-guided fractionation, and the structures were elucidated by NMR and GC-MS as apiol and Z-ligustilide, isolated from L. hultenii and L. californicum… CONTINUE READING

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