Phytosterol consumption and the anabolic steroid boldenone in humans: A hypothesis piloted

  title={Phytosterol consumption and the anabolic steroid boldenone in humans: A hypothesis piloted},
  author={Martine M. Ros and Saskia S. Sterk and Hans Verhagen and Anton F. H. Stalenhoef and Niels de Jong},
  journal={Food Additives \& Contaminants},
  pages={679 - 684}
The presence of the anabolic steroid boldenone in animals has become a research topic as its occurrence is proposed to be a marker for illegal hormone administration. However, boldenone can also be formed from β-sitosterol, a phytosterol present in animal feed, as well as from endogenous sources. The observations in animals together with the increased consumption of phytosterol-enriched foods in the Western population led the authors to the hypothesis that consumption of phytosterol-enriched… 

Excretion of endogenous boldione in human urine: Influence of phytosterol consumption

Evidence of boldenone, nandrolone, 5(10)-estrene-3β-17α-diol and 4-estrene-3,17-dione as minor metabolites of testosterone in equine.

In vitro experiments involving the incubation of testosterone with horse liver microsomes, liver, adipose and muscle tissues, and adrenal cortex homogenates failed to provide evidence that these four substances are minor metabolites of testosterone.

Sitosterolemia—10 years observation in two sisters

Two sisters with the rare, autosomal recessive condition, sitosterolemia, are followed for over 10 years and treatment with a diet low in plant lipids plus ezetimibe to block the absorption of sterols corrected most of the clinical and biochemical signs of the disease.

Phytochemical Profiling of Ethanolic Leaves Extract of Ipomoea sepiaria (Koenig Ex. Roxb)

India is one of the richest countries in the world with large and wide varieties of medicinal plants and considered to be the motherland for many traditional plants of medicinal values. Nature has

The Queen of Green Medicines: Biochemistry and Pathophysiology – A Review

This review focuses on the beneficial effects such as medicinal, nutritional and spiritual properties of tulsi.

Ultra-high performance liquid chromatography coupled to triple quadrupole mass spectrometry detection of naturally occurring thiouracil in urine of untreated livestock, domesticated animals and humans

Urine samples of animals and humans with known and unknown clinical backgrounds were analysed for thiouracil with a newly developed ultra-high performance liquid chromatography coupled to a triple quadrupole mass spectrometric analysis method without derivatisation to demonstrate the natural occurrence of thaviouracil in urine of animalsand humans.


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Presence and metabolism of the anabolic steroid boldenone in various animal species: a review

There was a necessity for further research to distinguish between naturally occurring and illegally usedboldenone forms, and the confirmation of the presence of boldenone metabolites (free and conjugated forms) in certain matrices of animals is proposed as a marker for the illegal treatment with Boldenone.

Endogenous occurrence of some anabolic steroids in swine matrices

The results give a well-documented overview of the status of the presence of these hormones in swine and illustrate that uncastrated ‘old’ boars produce the highest percentage of ‘positive’ matrices, followed by the cryptorchids, and urine samples from an intersex pig contains a higher concentration of nortestosterone than sows and can therefore be suspected for illegal use ofThese hormones.

Effectiveness of customary use of phytosterol/-stanol enriched margarines on blood cholesterol lowering.

Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels.

Present evidence is sufficient to promote use of sterols and stanols for lowering LDL cholesterol levels in persons at increased risk for coronary heart disease.

Comparison of the effects of plant sterol ester and plant stanol ester-enriched margarines in lowering serum cholesterol concentrations in hypercholesterolaemic subjects on a low-fat diet

STAEST and STEEST margarines reduced significantly and equally serum total and LDL cholesterol concentrations as part of a low-fat diet.

The cardiac toxicity of anabolic steroids.

Rapeseed oil, olive oil, plant sterols, and cholesterol metabolism: an ileostomy study

Rapeseed oil, tends to decrease cholesterol absorption, increases excretion of cholesterol and bile acids, increases serum marker of bile acid synthesis, and decreases serum levels of cholesterol compared to olive oil.

Intake of dietary plant sterols is inversely related to serum cholesterol concentration in men and women in the EPIC Norfolk population: a cross-sectional study

In a free-living population, a high intake of plant sterols is inversely associated with lower concentrations of total and low-density lipoprotein serum cholesterol, which may partly explain diet-related effects on serum cholesterol concentration.

Non-cholesterol sterols in serum, lipoproteins, and red cells in statin-treated FH subjects off and on plant stanol and sterol ester spreads.

Postlaunch Monitoring of Functional Foods - Methodology development (I)

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