Phytoestrogenic Isoflavones Daidzein and Genistein Reduce Glucose‐Toxicity‐Induced Cardiac Contractile Dysfunction in Ventricular Myocytes

@article{Hintz2004PhytoestrogenicID,
  title={Phytoestrogenic Isoflavones Daidzein and Genistein Reduce Glucose‐Toxicity‐Induced Cardiac Contractile Dysfunction in Ventricular Myocytes},
  author={K. K. Hintz and Jun Ren},
  journal={Endocrine Research},
  year={2004},
  volume={30},
  pages={215 - 223}
}
Epidemiological evidence suggests a reduction in the incidence of coronary heart disease, cancer and osteoporosis in populations with a high dietary intake of plant estrogen or phytoestrogen. [...] Key Method Adult rat ventricular myocytes were isolated and maintained for 24 hours in normal (NG, 5.5 mM) or high glucose (HG, 25.5 mM) medium in the absence or presence of isoflavones daidzein (50 microM) or genistein (20 microM).Expand
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