Phytoestrogen Content and Estrogenic Effect of Legume Fodder

@article{Saloniemi1995PhytoestrogenCA,
  title={Phytoestrogen Content and Estrogenic Effect of Legume Fodder},
  author={Hannu Saloniemi and Kristiina W{\"a}h{\"a}l{\"a} and P{\"a}ivi Nyk{\"a}nen-Kurki and Kaarlo Kallela and Ilkka Saastamoinen},
  journal={Proceedings of the Society for Experimental Biology and Medicine},
  year={1995},
  volume={208},
  pages={13 - 17}
}
Abstract This study is a summary of Finnish investigations of the phytoestrogen content of legume plants, red clover, white clover, alfalfa, and goat's rue. In addition to the chemical analyses, biological studies were performed. Uterine weight of immature rats was used as an indicator of the estrogenic effect of the fodder used. All red clover varieties studied contained estrogenic isoflavones, especially formononetin and biochanin-A. The phytoestrogen content varied from 1.0% to 2.5% of dry… 

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References

SHOWING 1-10 OF 22 REFERENCES

The effect of storage on the estrogenic effect of red clover silage.

  • K. Kallela
  • Biology, Medicine
    Nordisk veterinaermedicin
  • 1975
TLDR
The estrogenic effect of the silage fodder made from the red clover of 1973 varied considerably; in some samples it was greater but in most it was smaller than the estrogen effect ofThe fresh red clovers of 1972.

The oestrogenic isoflavones of subterranean clover

TLDR
A method of thin-layer chromatography has been developed which allows a rapid semiquantitative estimation of the main isoflavones present in this species of subterranean clover.

Urinary excretion of lignans and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional Japanese diet.

TLDR
The urinary excretion of lignans was low but that of the isoflavonoids was very high and correlated with soybean-product intake, suggesting that the low mortality in breast and prostate cancer of Japanese women and men may be due to the high intake of soybean products.

Plant oestrogens; the cause of decreased fertility in cows. A case report.

During the stall feeding period 1982-1983, it was established that serious fertility disturbances, indicating oestrogenic stimulation, had occurred in a herd of cattle in an area supported by the

Dietary fiber, phytoestrogens, and breast cancer.

TLDR
There is mounting evidence that dietary fiber has a protective effect and may favorably modify the enhanced breast cancer risk associated with the typical American high-fat low-fiber diet.

Variations in the Content of Plant Oestrogens in Red Clover-Timothy-Grass during the Growing Season

TLDR
A strong correlation between the plant oestrogen and crude protein contents of red clover is found, apparently both are due much to the same factors despite their divergent chemical compositions.

The effect of plant development and environment on formononetin concentration in red clover (Trifolium pratense L.)

Formononetin concentration in red clover herbage, determined by high performance liquid chromatography, was assessed in field, greenhouse and growth cabinet experiments. Formononetin content

Varietal variation in the isoflavone content of subterranean clover: Its estimation by a microtechnique

The isoflavone content of 46 subterranean clover varieties was estimated by a microtechnique which allowed of the semiquantitative analysis of 100 leaf samples per day. The relative proportions of