Phytoecdysteroids from the stem bark of Vitex doniana and their anti-inflammatory effects.

  title={Phytoecdysteroids from the stem bark of Vitex doniana and their anti-inflammatory effects.},
  author={Charles O. Ochieng and I. Ishola and Sylvia A. Opiyo and L. Manguro and P. Owuor and Keng-Chong Wong},
  journal={Planta medica},
  volume={79 1},
  • Charles O. Ochieng, I. Ishola, +3 authors Keng-Chong Wong
  • Published 2013
  • Chemistry, Medicine
  • Planta medica
  • With reference to the ethnopharmacological significance of Vitex doniana Sweet (Lamiaceae) leaves in the treatment of stomach and rheumatic pains as well as inflammatory disorders, biological studies on its stem bark extracts have also reported anti-inflammatory and analgesic activities, with no attempt to identify the active components. Chromatographic and spectroscopic procedures identified three new phytoecdysteroids: 21-hydroxyshidasterone (1), 11β-hydroxy-20-deoxyshidasterone (2), and 2,3… CONTINUE READING
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