Phytochemicals as cell cycle modulators--a less toxic approach in halting human cancers.

@article{Singh2002PhytochemicalsAC,
  title={Phytochemicals as cell cycle modulators--a less toxic approach in halting human cancers.},
  author={Rana P Singh and Sivanandhan Dhanalakshmi and Rajesh Agarwal},
  journal={Cell cycle},
  year={2002},
  volume={1 3},
  pages={156-61}
}
The multistep nature of cancer development provides a rationale for cancer prevention. Activation of oncogenes, inactivation of tumor suppressor genes and modulation of mitogenic signal transduction pathways are critical in cancer progression and present attractive targets for cancer prevention/intervention. In this respect, cell cycle regulation and its modulation by various natural (plant-derived) and synthetic agents are gaining widespread attention in recent years. A number of… CONTINUE READING

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