Phytochemical flavones isolated from Scutellaria barbata and antibacterial activity against methicillin-resistant Staphylococcus aureus.

Abstract

A crude extract prepared from Scutellaria barbata D. Don (Lamiaceae) was analyzed in the effort to discover antibacterial compounds against high-level strains of methicillin-resistant Staphylococcus aureus (MRSA). Apigenin and luteolin were isolated from the plant as active constituents against the bacteria. These flavonoid congeners were selectively toxic to S. aureus, including the MRSA and methicillin-sensitive S. aureus strains.

0200400'04'05'06'07'08'09'10'11'12'13'14'15'16'17
Citations per Year

830 Citations

Semantic Scholar estimates that this publication has 830 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Sato2000PhytochemicalFI, title={Phytochemical flavones isolated from Scutellaria barbata and antibacterial activity against methicillin-resistant Staphylococcus aureus.}, author={Yuji Sato and Shunkai Suzaki and Takeshi Nishikawa and Mikihiro Kihara and Hirotaka Shibata and Tomihiko Higuti}, journal={Journal of ethnopharmacology}, year={2000}, volume={72 3}, pages={483-8} }