Phytochemical and antiulcerogenic properties of rhizomes from Simaba ferruginea St. Hill. (Simaroubaceae).

  title={Phytochemical and antiulcerogenic properties of rhizomes from Simaba ferruginea St. Hill. (Simaroubaceae).},
  author={V{\^a}nia Floriani Noldin and Domingos Tabajara de Oliveira Martins and C{\'e}sar Marcos Marcello and Joaquim Corsino da Silva Lima and Franco delle Monache and Valdir Cechinel Filho},
  journal={Zeitschrift fur Naturforschung. C, Journal of biosciences},
  volume={60 9-10},
Simaba ferruginea (Simaroubaceae) is a Brazilian medicinal plant used in traditional medicine to treat several ailments, including gastric ulcers, fever, diarrhea, and dolorous and inflammatory processes. This study examines the chemical composition and antiulcerogenic effects of rhizomes from this plant. Bioassay-guided fractionation led to the isolation of two bioactive indole alkaloids called canthin-6-one (1) and 4-methoxycanthin-6-one (2). The alkaloid fraction and both alkaloids… CONTINUE READING


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