Phytochemical and Biological Studies of Paeoniaceae

@article{He2010PhytochemicalAB,
  title={Phytochemical and Biological Studies of Paeoniaceae},
  author={Chunnian He and Yong Peng and Yao Zhang and Li-jia Xu and J. Gu and P. Xiao},
  journal={Chemistry \& Biodiversity},
  year={2010},
  volume={7}
}
by Chun-Nian Hea)b), Yong Penga)b), Yao-Chun Zhangc), Li-Jia Xua)b), Jing Gua)b), and Pei-Gen Xiao*a)b) a) Institute of Medicinal Plant Development, Chinese Academy of Medical Science, Peking Union Medical College, 151 Malianwa North Road, Beijing 100193, P. R. China (phone: þ86-10-63011294; e-mail: xiaopg@public.bta.net.cn) b) Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Peking Union Medical College), Ministry of Education, Beijing 100193, P. R… Expand
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Phytochemical variation among the traditional Chinese medicine Mu Dan Pi from Paeonia suffruticosa (tree peony).
TLDR
Interestingly, the majority of investigated cultivars had relatively higher metabolite contents compared to the traditional medicinal tree peony cultivars. Expand
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It is necessary to carefully consider the origin of Paeonia germplasm when selecting medicinal materials to be used as resources for the production of PRR. Expand
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TLDR
The study indicates that the leaves of P. 'Hexie' have the potential to be a worthy medicinal substitute to Paeonia roots due to their high monoterpene glycosides, phenols, and flavonoids as well as their strong antioxidant capacity. Expand
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It could be concluded that the UPLC-QTOF-MS combined with chemometric methods could efficiently identify the three TCM drugs, and was a powerful approach for the chemical profiling of threeTCM drugs. Expand
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The polar methanolic extract (PPR), its n-BuOH soluble fraction and constituents of Paeonia rockii were extensively investigated and both extracts and some of their compounds have the ability to scavenge free-radicals and to inhibit Candida albicans growth. Expand
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TLDR
The data presented here provide new insights into both the medicinal and edible potential of roots from wild peony species. Expand
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Resveratrol Trimers from Seed Cake of Paeonia rockii
TLDR
In the course of screening natural products for antibacterial activities, a total acetone extract of the seed cake of Paeonia rockii showed significant effects against bacterial strains, resulting in the isolation and identification of five resveratrol trimers, including rockiiol C, gnetin H and suffruticosol A, which exhibited strong antib bacterial activities against Gram-positive bacteria. Expand
Genus Paeonia: A comprehensive review on traditional uses, phytochemistry, pharmacological activities, clinical application, and toxicology.
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A large number of phytochemical and pharmacological reports have indicated that Paeonia is an important medicinal herb resource, and some of its traditional uses including the treatment of inflammation and cardiovascular diseases and its use as a neuroprotective agent have been partially confirmed through modern pharmacological studies. Expand
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References

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Phytochemical and Pharmacological Studies on Chinese Paeonia Species
A new monoterpene glycoside, mudanpioside J (3), was isolated from the root cortex of Paeonia suffruticosa. Its structure has been established on the basis of spectral evidence. In addition, sixExpand
Chemical studies on the oriental plant drugs—XXXIII : The absolute structures of paeoniflorin, albiflorin, oxypaeoniflorin and benzoylpaeoniflorin isolated from chinese paeony root
The absolute structure of paeoniflorin, a major principle of Chinese Paeony root (Paonia albiflora Pallas (Paeoniaceae)) was established as I and as shown in Chart 2 by the X-ray analysis of a bromoExpand
Galloyl-oxypaeoniflorin, suffruticosides A, B, C, and D, five new antioxidative glycosides, and suffruticoside E, A paeonol glycoside, from Chinese moutan cortex.
Five new antioxidative glycosides named galloyl-oxypaeoniflorin, suffruticosides A, B, C, and D, and a new paeonol glycoside named suffruticoside E have been isolated from Chinese Moutan Cortex, theExpand
Effects and mechanisms of Paeoniflorin, a bioactive glucoside from paeony root, on adjuvant arthritis in rats
TLDR
PF suppresses rat AA at least partly by inhibiting abnormal proliferation of synoviocytes and the production of IL-1, PGE2, IL-6, VEGF and GM-CSF by synovocytes and reducing Gi and COX-2 expression in synovium. Expand
Two novel compounds from Paeonia suffructicosa.
TLDR
A new hexacyclic triterpenoid, mudanpinoic acid A, and a new gallic acid glycoside, mudanoside B, along with nine known compounds were isolated from the dried root cortex of Paeonia suffruticosa. Expand
Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway.
TLDR
The results showed that the water-extract of Paeoniae Radix (PRE) had inhibitory effect on the growth of both HepG2 and Hep3B cell lines, indicating that the cytotoxicity of PRE to the hepatoma cells is through activation of the cell death program, apoptosis. Expand
Chemical taxonomy of the Xibei tree peony from China by floral pigmentation
TLDR
The result suggests that the Xibei tree peony originated mainly from P. rockii, while Ward’s minimum-variance cluster analysis with principal component analysis produced a dendrogram using standardized scores of 20 pigment variables. Expand
Studies on active substances in herbs used for oketsu ("stagnant blood") in Chinese medicine. VI. On the anticoagulative principle in paeoniae radix.
The anticoagulative principles were isolated from Curcumae Rhizoma by a combination of partition and column chromatographies on silica gel, and identified as 1, 7-bis (4-hydroxy-3-methoxyphenyl)-1,Expand
Antihyperglycemic Activity of Herb Extracts on Streptozotocin-Induced Diabetic Rats
TLDR
Serum concentrations of liver-function marker enzymes, GOT and GPT, were restored by Rhus verniciflua (50 mg/kg) supplementation in diabetic rats, and blood TBARS concentrations, the products of glucose oxidation in blood, were lowered. Expand
Triterpenoids from callus tissue cultures of Paeonia species
TLDR
Six triterpenoids were isolated from the callus tissues of Paeonia japonica, P. lactiflora and P. suffruticosa and the postulated biosynthetic sequence of these compounds is discussed and the triter penoids produced from the three callus tissue have been compared from a chemotaxonomical standpoint. Expand
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