Phytochemical analysis and genetic characterization of six Hypericum species from Serbia.

  title={Phytochemical analysis and genetic characterization of six Hypericum species from Serbia.},
  author={Andrija {\vS}melcerovi{\'c} and Vijeshwar Verma and Michael Spiteller and Syed Mudasir Ahmad and Satish Chander Puri and Ghulam Nabi Qazi},
  volume={67 2},
Chemical composition of Hypericum pruinatum Boiss. and Bal. from wild populations of Northern Turkey
The present study was conducted to determine the variation in the content of several plant chemicals, namely hyperforin, hypericin, pseudohypericin, chlorogenic acid, rutin, hyperoside,
Between Species Diversity of Hypericum Perforatum and H. maculatum by the Content of Bioactive Compounds
The objective of present study was to establish and compare the contents of secondary metabolites of two Hypericum species, H. perforatum and H. maculatum, native to Lithuania, and to evaluate
Hypericin and Pseudohypericin Contents in Some Hypericum. Species Growing in Turkey
Hypericin and pseudohypericin content in stems, leaves, and flowers of some Hypericum species growing in Turkey, namely, H. heterophyllum, was determined by HPLC and H. triquetrifolium.
Water-alcoholic extracts of H. hirsutum samples collected at four localities in Vojvodina by liquid chromatography (HPLC-DAD) suggest a good match (in a term of a presence of investigated compounds) of previously published results describing chemical profile of H perforatum, and chemotaxonomic analysis showed variations in quantity of secondary metabolites in the examined extracts.
Genetic characterization and biochemical analysis in the populations of P. corylifolia L. from Western Maharashtra.
An attempt has been made for the first to correlate the genetic and biochemical data in the populations of P. corylifolia to show better discriminating power of RAPD’s in the present study.
Variability of Hypericins and Hyperforin in Hypericum Species from the Sicilian Flora
A carefully planned cultivation of Hypericum seems the best option to achieve high and steady biomass yields, but there is a need for phytochemical studies, aimed to identify for multiplication the genotypes with the highest content of the active metabolites.
Ecologically and ontogenetically induced variations in phenolic compounds and biological activities of Hypericum maculatum subsp. maculatum, Hypericaceae
All the extracts exhibited notable antioxidant potential in the used test systems as well as the ability to inhibit AChE and α-amylase, which explored potential use of plant in the treatments of diabetes and Alzheimer’s disease.


Quantitative phytochemical analyses of six hypericum species growing in slovenia.
The 74 samples of six HYPERICUM species were collected around Slovenia and analysed for the content of ten substances, finding Rutin and hyperoside are in positive correlation, and quercitrin is in negative correlation with the altitude of the growing site.
Phytochemical analysis of nine Hypericum L. species from Serbia and the F.Y.R. Macedonia.
The methanol extracts of the aerial parts of nine Hypericum species were obtained by accelerated solvent extraction (ASE) and analyzed for the content of four constituents (hyperoside, quercitrin, hyperforin and hypericin) by LC-MS/ MS.
Inter‐population variability of secondary metabolites in Hypericum spp. (Hypericaceae) of the Northern Apennines, Italy
No significant effects of environmental factors on active compound production were observed, except for the rutin content which is in positive correlation with the altitude of the growing site.
Hypericin and pseudohypericin in some Hypericum species.
  • Kitanov
  • Biology, Medicine
    Biochemical systematics and ecology
  • 2001
Production of hypericin, pseudohypericin and flavonoids in cell cultures of various Hypericum species and their chemotypes.
The flavonoid patterns, comprising monomeric quercetin derivatives and dimeric apigenin derivatives, varied among strains over a wide range and in general, the pseudohypericin content was significantly higher than that of hypericin.
RAPD analysis: a method to investigate aspects of the reproductive biology of Hypericum perforatum L.
It is concluded that RAPD fingerprint analysis is a suitable technique to discover identity or non-identity in H. perforatum populations and may be used in addition to cytological studies to confirm the mode of reproduction by apomixis versus self-pollination, haploid parthenogenesis or cross-fertilization.
Genetic profiling of Hypericum (St. John's Wort) species by nuclear ribosomal ITS sequence analysis.
A PCR-based DNA amplification method was applied to genetically distinguish the popular dietary supplement Hypericum perforatum L. (common St. John's Wort) from other related Hypericum species, revealing three strongly supported monophyletic clades, plus several secondary monophylettic groupings.
Hypericum perforatum--chemical profiling and quantitative results of St. John's Wort products by an improved high-performance liquid chromatography method.
The analysis of flavonoids, naphthodianthrones, and the phloroglucinol derivative hyperforin in H. perforatum is described and qualitative and quantitative results are discussed.
Modes of reproduction in Australian populations of Hypericum perforatum L. (St. John's wort) revealed by DNA fingerprinting and cytological methods.
The results are discussed in relation to the management of invasive populations, and the implications for plant breeding and production of St. John's wort for medicinal purposes.