Phytochemical Study and Evaluation of the Cytotoxic Properties of Methanolic Extract from Baccharis obtusifolia

  title={Phytochemical Study and Evaluation of the Cytotoxic Properties of Methanolic Extract from Baccharis obtusifolia},
  author={Juan Carlos Romero-Benavides and Gina C Ortega-Torres and Javier Villacis and Sara L. Vivanco-Jaramillo and Karla I Galarza-Urgil{\'e}s and Natalia Bail{\'o}n-Moscoso},
  journal={International Journal of Medicinal Chemistry},
Some species of the Baccharis genus have been shown to possess important biomedical properties, including cytotoxic activity. In this study, we examined the cytotoxic effect of methanol extract from Baccharis obtusifolia (Asteraceae) in cancer cell lines of prostate (PC-3), colon (RKO), astrocytoma (D-384), and breast (MCF-7). The methanolic extract displayed the largest substantial cytotoxic effect in lines of colon cancer (RKO) and cerebral astrocytoma (D-384). Chromatographic purification of… 

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