The crude methanol extract of different parts of Bougainvillea glabra were experimented and examined for its Phytochemical Constituents and Antibacterial Activity Index with four Commercial Antibiotics against 4 bacterial strains. Phytochemical screening revealed the presence of alkaloids, saponins, tannins, reducing sugar and cardiac glycosides in the leaves of Bougainvillea glabra. Antrhaquinones, flavonoids and terpenoids were absent in the leaves of Bougainvillea glabra. Different parts of Bougainvillea glabra have shown antibacterial potentials when used on two gram-positive bacteria, the Bacillus Subtilis and Staphylococcus aureus; and two gram-negative bacteria, the Escherichia coli and Pseudomonas aeruginosa except for flowers against two gram-positive bacteria, the Bacillus Subtilis and Staphylococcus aureus. Results show that this plant is an interesting source of antimicrobial agents, potential source of nutraceuticals, anti-inflammatory, antiallergenic, antithrombic, antiviral, analgesic, antimycotic, virostatic and other pharmacological importance.