Phytochemical, antimicrobial and antiprotozoal evaluation of Garcinia mangostana pericarp and α-mangostin, its major xanthone derivative.

@article{AlMassarani2013PhytochemicalAA,
  title={Phytochemical, antimicrobial and antiprotozoal evaluation of Garcinia mangostana pericarp and α-mangostin, its major xanthone derivative.},
  author={Shaza Mohamed Al-Massarani and Ali A. El Gamal and Nawal M. Al-Musayeib and Ramzi A Mothana and Omer Ahmed Basudan and Adnan Jathlan Al-Rehaily and Mohamed Farag and Mahmoud H Assaf and Kamaleldin H El Tahir and Louis Maes},
  journal={Molecules},
  year={2013},
  volume={18 9},
  pages={10599-608}
}
Five xanthone derivatives and one flavanol were isolated from the dichloromethane extract of Garcinia mangostana. Dichloromethane, ethyl acetate extract and the major xanthone (α-mangostin) were evaluated in vitro against erythrocytic schizonts of Plasmodium falciparum, intracellular amastigotes of Leishmania infantum and Trypanosoma cruzi and free trypomastigotes of T. brucei. The major constituent α-mangostin was also checked for antimicrobial potential against Candida albicans, Escherichia… CONTINUE READING

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