Phyto-pharmacological potential of Jaiphal (Myristica fragrans Houtt): A spice of medicinal importance and its utilization in Unani Medicine

@article{Hamiduddin2018PhytopharmacologicalPO,
  title={Phyto-pharmacological potential of Jaiphal (Myristica fragrans Houtt): A spice of medicinal importance and its utilization in Unani Medicine},
  author={Hamiduddin},
  journal={International Journal of Green Pharmacy},
  year={2018},
  volume={12}
}
  • Hamiduddin
  • Published 18 May 2018
  • Medicine
  • International Journal of Green Pharmacy
Jaiphal is a common fruit of Myristica fragrans Houtt. plant used as spices as well as for medicinal purpose in Unani System of Medicine since antiquity. The Saydalaneh (pharmacist) in Arab introduce a large number of new drugs to clinical use including nutmeg. As a Unani concept of temperament, it is hot and dry. It is very common and popular drug used as digestive, carminative, appetizer, exhilarant and mood elevator, antitussive, antiemetic, demulcent, aphrodisiac, stomachic, liver, nervine… 
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References

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Phytochemistry and pharmacologic properties of Myristica fragrans Hoyutt.: A review
TLDR
This article presents comprehensive analyzed information on the botanical, chemical and pharmacological aspects of M. fragrans, which has recently been shown to have antioxidant, anticonvulsant, analgesic, anti-inflammatory, antidiabetic, antibacterial and antifungal activities.
Pharmacological studies on Myristica fragrans--antidiarrheal, hypnotic, analgesic and hemodynamic (blood pressure) parameters.
TLDR
Overall extracts of nutmeg showed a good antidiarrheal effect, with a significant sedative property, with no harmful effects on blood pressure and ECG.
Antioxidant properties of Myristica fragrans (Houtt) and its effect on selected organs of albino rats
Aqueous extract of the seed of Myristica fragrans (nutmeg) was evaluated for its phytochemical constituents, antinutrients and antioxidant properties. Toxicological investigation was also carried out…
Aphrodisiac activity of 50% ethanolic extracts of Myristica fragrans Houtt. (nutmeg) and Syzygium aromaticum (L) Merr. & Perry. (clove) in male mice: a comparative study
TLDR
The extracts of the nutmeg and clove were found to stimulate the mounting behaviour of male mice, and also to significantly increase their mating performance, and were devoid of any conspicuous general short term toxicity.
Effects of ethanolic extract of Myristica fragrans Houtt. (nutmeg) on some heamatological indices in albino rats
TLDR
The results showed significant decreases in red blood cell (RBC) count, packed cell volume (PCV), haemoglobin concentration (HbC) and platelet count especially at high doses, which seems to confirm the anti-inflammatory properties of seed of M. fragrans and suggest that it may have deleterious effects on haemopoiesis at high dose.
Antifungal Activities and Essential Oil Constituents of Some Spices from Pakistan
TLDR
Hydrodistillation of Amomum subulatum, Cinnamomum verum, Coriandrum sativum, Cuminum cyminum, Elettaria cardamommum, Myristica fragrans (Mace), and Myristicas fragran (Nutmeg) purchased from local spice markets yielded essential oils which contained 1,8-cineole and cinnamaldehyde, respectively, as main constituents determined by GC/MS.
Antibacterial principles from Myristica fragrans seeds.
TLDR
All the constituents isolated from nutmeg exhibited good antibacterial activity, which shows the potential of natural compounds in replacement of synthetic preservatives.
Antimutagenic effects of aqueous fraction of Myristica fragrans (Houtt.) leaves on Salmonella typhimurium and Mus musculus.
TLDR
In vitro and in vivo mutagenic and antimutagenic effects of aqueous fraction of Myristica fragrans leaves on TA100 strain of Salmonella typhimurium and Mus musculus are evaluated, and AFMF seems to contain a promising chemotherapeutic agent for the prevention of genetic damage that is crucial for cancer development.
Chemical Constituents and Activities of the Essential Oil from Myristica fragrans against Cigarette Beetle Lasioderma serricorne
TLDR
The results indicate that the essential oil of M. fragrans and its active constituents have potential for development as natural insecticides and repellents to control L. serricorne.
Hepatoprotective effect of myristicin from nutmeg (Myristica fragrans) on lipopolysaccharide/d-galactosamine-induced liver injury.
TLDR
Findings suggest that the hepatoprotective activity of myristicin might be, at least in part, due to the inhibition of TNF-alpha release from macrophages, however, further studies are needed to elucidate the hepatOProtective mechanism(s).
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