• Corpus ID: 12884667

Phytic acid down-regulates IL-8 secretion from colonic epithelial cells by influencing mitogen-activated protein kinase signaling pathway.

@article{Wawszczyk2012PhyticAD,
  title={Phytic acid down-regulates IL-8 secretion from colonic epithelial cells by influencing mitogen-activated protein kinase signaling pathway.},
  author={Joanna Wawszczyk and Arkadiusz Orchel and Małgorzata Kapral and Andrzej Hollek and Ludmiła Wȩglarz},
  journal={Acta poloniae pharmaceutica},
  year={2012},
  volume={69 6},
  pages={
          1276-82
        }
}
Phytic acid (IP6) is an essential component of high fiber diet physiologically present in human large gut. It has been recognized to possess various significant health benefits effects including chemopreventive and have antineoplastic activity against various types of cancer. Moreover, its role in immune response through modulation of the secretion of proinflammatory cytokines and chemokines has been postulated. One of the signal transduction pathways involved in a variety of inflammatory… 
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