Physiopathology of splanchnic vasodilation in portal hypertension.

  title={Physiopathology of splanchnic vasodilation in portal hypertension.},
  author={Mar{\'i}a Martell and M Regina Coll and Nahia Ezkurdia and Imma Raurell and Joan Genesc{\`a}},
  journal={World journal of hepatology},
  volume={2 6},
In liver cirrhosis, the circulatory hemodynamic alterations of portal hypertension significantly contribute to many of the clinical manifestations of the disease. In the physiopathology of this vascular alteration, mesenteric splanchnic vasodilation plays an essential role by initiating the hemodynamic process. Numerous studies performed in cirrhotic patients and animal models have shown that this splanchnic vasodilation is the result of an important increase in local and systemic vasodilators… CONTINUE READING
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