Physiology of thermoregulatory dysfunction and current approaches to the treatment of vasomotor symptoms.

@article{Deecher2005PhysiologyOT,
  title={Physiology of thermoregulatory dysfunction and current approaches to the treatment of vasomotor symptoms.},
  author={Darlene C. Deecher},
  journal={Expert opinion on investigational drugs},
  year={2005},
  volume={14 4},
  pages={435-48}
}
Vasomotor symptoms (VMS), including hot flushes and night sweats, are the most common symptoms associated with menopause. Although the physiology of hot flushes is not fully defined, understanding the complex thermoregulatory circuitry that underlies VMS is important for the development of new therapies. This circuitry is composed of three distinct, yet interconnected, components: core body temperature, neurochemical messaging and peripheral vasculature. Evidence suggests that multiple… CONTINUE READING

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