Physiology of the prion protein.

@article{Linden2008PhysiologyOT,
  title={Physiology of the prion protein.},
  author={R. Linden and V. R. Martins and M. Prado and M. Cammarota and I. Izquierdo and R. Brentani},
  journal={Physiological reviews},
  year={2008},
  volume={88 2},
  pages={
          673-728
        }
}
Prion diseases are transmissible spongiform encephalopathies (TSEs), attributed to conformational conversion of the cellular prion protein (PrP(C)) into an abnormal conformer that accumulates in the brain. Understanding the pathogenesis of TSEs requires the identification of functional properties of PrP(C). Here we examine the physiological functions of PrP(C) at the systemic, cellular, and molecular level. Current data show that both the expression and the engagement of PrP(C) with a variety… Expand
Understanding the neurospecificity of Prion protein signaling.
Prion protein: orchestrating neurotrophic activities.
Possible role for Ca2+ in the pathophysiology of the prion protein?
Tyrosine hydroxylase and HSPB8 interact with the prion protein
Prion protein at the crossroads of physiology and disease
Allosteric function and dysfunction of the prion protein
Physiological Functions of the Cellular Prion Protein
The prion protein in neuroimmune crosstalk
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 636 REFERENCES
Prion protein induced signaling cascades in monocytes.
Towards cellular receptors for prions
Role of the 37 kDa laminin receptor precursor in the life cycle of prions.
  • R. Rieger, C. Lasmézas, S. Weiss
  • Medicine, Biology
  • Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
  • 1999
The highways and byways of prion protein trafficking.
Evolving views in prion glycosylation: functional and pathological implications.
The role of the cellular prion protein in the immune system
Prion protein glycosylation
...
1
2
3
4
5
...