Physiology of isolated gastric endocrine cells.

  title={Physiology of isolated gastric endocrine cells.},
  author={George Sachs and N M Zeng and Christian Prinz},
  journal={Annual review of physiology},
The regulation of gastric acid secretion is achieved in the periphery by interplay between three major gastric endocrine cells: the enterochromaffin-like (ECL) cell, the gastrin or G cell, and the somatostatin or D cell. Regulation of these cells is via stimulatory or inhibitory paracrine, endocrine, and neural pathways. Upregulation of ECL function is determined by activation of CCK-B receptors, by gastrin, and by activation of beta-adrenergic receptors, as well as by acetylcholine in some (10… CONTINUE READING


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