Physiology of cell volume regulation in vertebrates.

  title={Physiology of cell volume regulation in vertebrates.},
  author={Else Kay Hoffmann and Ian H Lambert and Stine Falsig Pedersen},
  journal={Physiological reviews},
  volume={89 1},
The ability to control cell volume is pivotal for cell function. Cell volume perturbation elicits a wide array of signaling events, leading to protective (e.g., cytoskeletal rearrangement) and adaptive (e.g., altered expression of osmolyte transporters and heat shock proteins) measures and, in most cases, activation of volume regulatory osmolyte transport. After acute swelling, cell volume is regulated by the process of regulatory volume decrease (RVD), which involves the activation of KCl… CONTINUE READING
Highly Influential
This paper has highly influenced 73 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 440 extracted citations


Publications referenced by this paper.
Showing 1-10 of 10 references

Physiology of Cell Volume Regulation in Vertebrates

  • EK Hoffmann, IH Lambert, SF Pedersen
  • Physiol Rev
  • 2009

Similar Papers

Loading similar papers…