Physiology of apoptosis.

  title={Physiology of apoptosis.},
  author={Erich Gulbins and Andreas Jekle and Klaus Ferlinz and Heike Grassm{\'e} and Florian Lang},
  journal={American journal of physiology. Renal physiology},
  volume={279 4},
Ion fluxes and volume changes of the whole cell as well as of organelles belong to the hallmarks of apoptosis; however, the molecular mechanism regulating these changes is only poorly characterized. Several ion channels in the plasma membrane, in particular the N-type K(+) channel, the chloride channel cystic fibrosis conductance regulator, and an outward rectifying chloride channel, as well as the mitochondrial permeability transition pore, have been implicated to be involved in signal… CONTINUE READING

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