Physiology of IgD. VII. Induction of receptors for IgD on cloned T cells by IgD and interleukin 2.

The role of IgD in the immune response has remained elusive, although the predominance of IgD on the B cell surface and the paucity of IgD in serum have suggested a receptor function. In support of this hypothesis, it has recently been shown that receptors for IgD on helper T cells can be induced by exposure to IgD in vivo and in vitro. Such IgD receptor… CONTINUE READING