Physiology of Angina and Its Alleviation With Nitroglycerin

  title={Physiology of Angina and Its Alleviation With Nitroglycerin},
  author={Kaleab N. Asrress and Rupert Nicholas Williams and Timothy P. E. Lockie and Muhammed Zeeshan Khawaja and Kalpa De Silva and Matthew Lumley and Tiffany Patterson and Satpal S Arri and Sana Ihsan and Howard Ellis and A. Le Guilcher and Brian Clapp and Philip J. Chowienczyk and Sven Plein and Divaka Perera and Michael Marber and Simon Robert Redwood},
BACKGROUND The mechanisms governing exercise-induced angina and its alleviation by the most commonly used antianginal drug, nitroglycerin, are incompletely understood. The purpose of this study was to develop a method by which the effects of antianginal drugs could be evaluated invasively during physiological exercise to gain further understanding of the clinical impact of angina and nitroglycerin. METHODS Forty patients (mean age, 65.2±7.6 years) with exertional angina and coronary artery… CONTINUE READING
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