Physiology and clinical significance of natriuretic hormones

  title={Physiology and clinical significance of natriuretic hormones},
  author={Sandeep Chopra and Davis Cherian and Prashant Paul Verghese and Jubbin Jagan Jacob},
  booktitle={Indian journal of endocrinology and metabolism},
The natriuretic system consists of the atrial natriuretic peptide (ANP) and four other similar peptides including the wrongly named brain natriuretic peptide (BNP). Chemically they are small peptide hormones predominantly secreted by the cardiac myocytes in response to stretching forces. The peptide hormones have multiple renal, hemodynamic, and antiproliferative effects through three different kinds of natriuretic receptors. Clinical interest in these peptide hormones was initially stimulated… CONTINUE READING