Physiology and Pathophysiology of Steroid Biosynthesis, Transport and Metabolism in the Human Placenta

@article{Chatuphonprasert2018PhysiologyAP,
  title={Physiology and Pathophysiology of Steroid Biosynthesis, Transport and Metabolism in the Human Placenta},
  author={W. Chatuphonprasert and K. Jarukamjorn and I. Ellinger},
  journal={Frontiers in Pharmacology},
  year={2018},
  volume={9}
}
The steroid hormones progestagens, estrogens, androgens, and glucocorticoids as well as their precursor cholesterol are required for successful establishment and maintenance of pregnancy and proper development of the fetus. The human placenta forms at the interface of maternal and fetal circulation. It participates in biosynthesis and metabolism of steroids as well as their regulated exchange between maternal and fetal compartment. This review outlines the mechanisms of human placental handling… Expand
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