Physiology, pharmacology and parasitology.

@article{Hennessy1997PhysiologyPA,
  title={Physiology, pharmacology and parasitology.},
  author={D. R. Hennessy},
  journal={International journal for parasitology},
  year={1997},
  volume={27 2},
  pages={
          145-52
        }
}
  • D. Hennessy
  • Published 1 February 1997
  • Biology
  • International journal for parasitology
Control of nematode parasites with agents acting on neuro-musculature systems: lessons for neuropeptide ligand discovery.
TLDR
The properties of existing agents that have been used to control nematode parasites and that have an action on neuromuscular systems are commented on and some warning signs for recognized but dangerous obstacles are provided.
Update on Parasite Control in Slllall Rulllinants 2006 Addressing the Challenges Posed by Multiple-Drug Resistant
TLDR
Unless veterinarians take an active and leading role in the education of small ruminant owners and help to implement these new approaches to parasite control, there may be no effective anthelmintics remaining when control fails, and any new technologies or developments in non-chemical GIN control methods will be less effective than chemical control.
Anthelmintic resistance in nematodes of horses.
  • R. Kaplan
  • Biology, Medicine
    Veterinary research
  • 2002
TLDR
The increasingly high prevalence of anthelmintic-resistant cyathostomes must be taken into account when designing worm control programs for horses, and strategies to decelerate further selection for drug resistance thereby extending the lifetime of currently effective anthel mintics should be implemented whenever possible.
Principles for the use of macrocyclic lactones to minimise selection for resistance
Objective To provide principles for the appropriate use of avermectin/milbemycin or macrocyclic lactone (ML) anthelmintics in sheep, to ensure effective worm control and to minimise selection for ML
Total Anthelmintic Failure to Control Nematode Parasites of Small Ruminants on Government Breeding Farms in Sabah, East Malaysia
TLDR
Tests for anthelmintic efficacy using the faecal egg count reduction test (FECRT) on the range of drugs used to control nematode parasites showed a total failure of the benzimidazole, imidothiazole, macrocyclic lactone and salicylanilide groups of anthel mintics to control H. contortus infections of sheep and goats on all farms.
Evaluation of prevalence and clinical implications of anthelmintic resistance in gastrointestinal nematodes in goats.
TLDR
Anthelmintic resistance in GINs of goats is highly prevalent in the southern United States and emphasizes the need for reexamination of nematode control practices.
3993 AABP 2021 Conference Proceedings Text v2.indd
Control of gastrointestinal (GIN) parasites is of primary concern in any small ruminant health management program, and is critical to profitability of the farm. For many years, GIN were controlled by
Kinetic disposition of albendazole in goats subclinically infected with gastrointestinal nematodes vis-à-vis naive animals following oral and intraruminal administration
TLDR
As the duration of exposure of parasites to the toxic concentration of the anthelmintically active metabolite was prolonged, it could be assumed that intraruminal delivery of the drug would improve the efficacy of albendazole in parasitized goats.
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References

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Anthelmintic resistance in Australia.
Anthelmintic resistance in Australian sheep nematode populations.
The resistance status of gastro-intestinal nematodes to anthelmintics was evaluated on 881 sheep farms throughout Australia during 1991-92. Resistance was shown to be widespread. Overall, 85% of
Resistance to synthetic pyrethroid pour-on insecticides in strains of the sheep body louse Bovicola (Damalinia) ovis.
TLDR
The pour-on SP treatments significantly reduced the lice population but failed to eliminate the infestation in 7 of 13 experiments in sheep carrying strains of lice with resistance factors of greater than 4 to at least one of the SP compounds.
The pharmacodynamics of ivermectin in sheep and cattle.
TLDR
It is hypothesized that the low efficacy of ivermectin against small intestinal nematode compared with abomasal nematodes is not due to differences in iverMectin concentrations in the predilection sites but is probably due to tachyphylaxis in the nematODE allowing the small intestinal Nematodes to re-establish before they have left theirpredilection site.
A survey of organophosphate susceptibility in populations of Bovicola ovis (Schrank) (Phthiraptera, Trichodectidae)
TLDR
A toxicological survey of field populations of the sheep body louse identified only one strain whose response to diazinon was recognisably separate from the normally distributed responses of the other strains, suggesting that a pyrethroid or propetamphos treatment would be the most appropriate control option.
Physiological and Pharmacological Aspects of the Reticulo-Rumen
TLDR
This workshop was organized and convened in an attempt to strengthen the basic science of the ruminant stomach, as it applies to an economically important group of mammals.
The occurrence of anthelmintic-resistant sheep nematodes in the southern North Island of New Zealand.
  • P. Mckenna
  • Biology, Medicine
    New Zealand veterinary journal
  • 1994
An analysis of veterinary diagnostic cases submitted to the Batchelar Animal Health Laboratory for faecal egg count reduction testing in sheep between 1986 and 1992 showed that 63% of them originated
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